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Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B

OBJECTIVE: The involvement of HBV DNA integration in promoting hepatocarcinogenesis and the extent to which the intrahepatic HBV reservoir modulates liver disease progression remains poorly understood. We examined the intrahepatic HBV reservoir, the occurrence of HBV DNA integration and its impact o...

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Detalles Bibliográficos
Autores principales: Svicher, Valentina, Salpini, Romina, Piermatteo, Lorenzo, Carioti, Luca, Battisti, Arianna, Colagrossi, Luna, Scutari, Rossana, Surdo, Matteo, Cacciafesta, Valeria, Nuccitelli, Andrea, Hansi, Navjyot, Ceccherini Silberstein, Francesca, Perno, Carlo Federico, Gill, Upkar S, Kennedy, Patrick T F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588301/
https://www.ncbi.nlm.nih.gov/pubmed/33402415
http://dx.doi.org/10.1136/gutjnl-2020-323300