Cargando…
Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B
OBJECTIVE: The involvement of HBV DNA integration in promoting hepatocarcinogenesis and the extent to which the intrahepatic HBV reservoir modulates liver disease progression remains poorly understood. We examined the intrahepatic HBV reservoir, the occurrence of HBV DNA integration and its impact o...
Autores principales: | Svicher, Valentina, Salpini, Romina, Piermatteo, Lorenzo, Carioti, Luca, Battisti, Arianna, Colagrossi, Luna, Scutari, Rossana, Surdo, Matteo, Cacciafesta, Valeria, Nuccitelli, Andrea, Hansi, Navjyot, Ceccherini Silberstein, Francesca, Perno, Carlo Federico, Gill, Upkar S, Kennedy, Patrick T F |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588301/ https://www.ncbi.nlm.nih.gov/pubmed/33402415 http://dx.doi.org/10.1136/gutjnl-2020-323300 |
Ejemplares similares
-
HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation
por: Piermatteo, Lorenzo, et al.
Publicado: (2021) -
An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression
por: Brancaccio, Giuseppina, et al.
Publicado: (2021) -
Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infection
por: Salpini, Romina, et al.
Publicado: (2020) -
Correlations of HBV Genotypes, Mutations Affecting HBeAg Expression and HBeAg/ anti-HBe Status in HBV Carriers
por: Lim, Chee Kent, et al.
Publicado: (2006) -
Cryptic HBV Replicative Activity Is Frequently Revealed in Anti-HBc-Positive/HBsAg-Negative Patients with HIV Infection by Highly Sensitive Molecular Assays, and Can Be Predicted by Integrating Classical and Novel Serological HBV Markers
por: Salpini, Romina, et al.
Publicado: (2020)