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Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro

Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promising alternative to conventional cytotoxic chemother...

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Detalles Bibliográficos
Autores principales: Josa-Culleré, Laia, Cogswell, Thomas J., Georgiou, Irene, Jay-Smith, Morgan, Jackson, Thomas R., Bataille, Carole J. R., Davies, Stephen G., Vyas, Paresh, Milne, Thomas A., Wynne, Graham M., Russell, Angela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588310/
https://www.ncbi.nlm.nih.gov/pubmed/34771052
http://dx.doi.org/10.3390/molecules26216648