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Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro
Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promising alternative to conventional cytotoxic chemother...
Autores principales: | Josa-Culleré, Laia, Cogswell, Thomas J., Georgiou, Irene, Jay-Smith, Morgan, Jackson, Thomas R., Bataille, Carole J. R., Davies, Stephen G., Vyas, Paresh, Milne, Thomas A., Wynne, Graham M., Russell, Angela J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588310/ https://www.ncbi.nlm.nih.gov/pubmed/34771052 http://dx.doi.org/10.3390/molecules26216648 |
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