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RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease

OBJECTIVE: Receptor-interacting protein kinase 3 (RIPK3) is a key player in necroptosis execution and an emerging metabolic regulator, whose contribution to non-alcoholic fatty liver disease (NAFLD) is controversial. We aimed to clarify the impact of RIPK3 signalling in the pathogenesis of human and...

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Detalles Bibliográficos
Autores principales: Afonso, Marta B, Rodrigues, Pedro M, Mateus-Pinheiro, Miguel, Simão, André L, Gaspar, Maria M, Majdi, Amine, Arretxe, Enara, Alonso, Cristina, Santos-Laso, Alvaro, Jimenez-Agüero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria Jesus, Banales, Jesus M, Ratziu, Vlad, Gautheron, Jeremie, Castro, Rui E, Rodrigues, Cecília M P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588316/
https://www.ncbi.nlm.nih.gov/pubmed/33361348
http://dx.doi.org/10.1136/gutjnl-2020-321767