Polyamines Upregulate Cephalosporin C Production and Expression of β-Lactam Biosynthetic Genes in High-Yielding Acremonium chrysogenum Strain

The high-yielding production of pharmaceutically significant secondary metabolites in filamentous fungi is obtained by random mutagenesis; such changes may be associated with shifts in the metabolism of polyamines. We have previously shown that, in the Acremonium chrysogenum cephalosporin C high-yie...

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Detalles Bibliográficos
Autores principales: Zhgun, Alexander A., Eldarov, Mikhail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588317/
https://www.ncbi.nlm.nih.gov/pubmed/34771045
http://dx.doi.org/10.3390/molecules26216636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588317/
https://www.ncbi.nlm.nih.gov/pubmed/34771045
http://dx.doi.org/10.3390/molecules26216636

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