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Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2H-pyrazolo[4,3-c]pyridines

A library of 2,4,6,7-tetrasubstituted-2H-pyrazolo[4,3-c]pyridines was prepared from easily accessible 1-phenyl-3-(2-phenylethynyl)-1H-pyrazole-4-carbaldehyde via an iodine-mediated electrophilic cyclization of intermediate 4-(azidomethyl)-1-phenyl-3-(phenylethynyl)-1H-pyrazoles to 7-iodo-2,6-dipheny...

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Detalles Bibliográficos
Autores principales: Razmienė, Beatričė, Řezníčková, Eva, Dambrauskienė, Vaida, Ostruszka, Radek, Kubala, Martin, Žukauskaitė, Asta, Kryštof, Vladimír, Šačkus, Algirdas, Arbačiauskienė, Eglė
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588486/
https://www.ncbi.nlm.nih.gov/pubmed/34771163
http://dx.doi.org/10.3390/molecules26216747