Cargando…

Chloroquine Potentiates the Anticancer Effect of Pterostilbene on Pancreatic Cancer by Inhibiting Autophagy and Downregulating the RAGE/STAT3 Pathway

The treatment of pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge, because pro-survival signaling pathways—such as the receptor for advanced glycation end products (RAGE)/signal transducer and activator of transcription 3 (STAT3) pathway—are overexpressed in PDAC cells. Moreover, PDA...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Rong-Jane, Lyu, Yi-Jhen, Chen, Yu-Ying, Lee, Yen-Chien, Pan, Min-Hsiung, Ho, Yuan-Soon, Wang, Ying-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588513/
https://www.ncbi.nlm.nih.gov/pubmed/34771150
http://dx.doi.org/10.3390/molecules26216741