Dexmedetomidine inhibits mitochondria damage and apoptosis of enteric glial cells in experimental intestinal ischemia/reperfusion injury via SIRT3-dependent PINK1/HDAC3/p53 pathway

BACKGROUND: Intestinal ischemia/reperfusion (I/R) injury commonly occurs during perioperative periods, resulting in high morbidity and mortality on a global scale. Dexmedetomidine (Dex) is a selective α2-agonist that is frequently applied during perioperative periods for its analgesia effect; howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, Liu, Xiao-Ming, Hu, Qian, Liu, Zheng-Ren, Liu, Zhi-Yi, Zhang, Huai-Gen, Huang, Yuan-Lu, Chen, Qiu-Hong, Wang, Wen-Xiang, Zhang, Xue-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588684/
https://www.ncbi.nlm.nih.gov/pubmed/34772407
http://dx.doi.org/10.1186/s12967-021-03027-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588684/
https://www.ncbi.nlm.nih.gov/pubmed/34772407
http://dx.doi.org/10.1186/s12967-021-03027-6

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