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EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2

OBJECTIVE: Growth factors [transforming growth factor-β (TGF-β), epidermal growth factor (EGF), endothelin-1 (ET- 1)] stimulate proteoglycan synthesis resulting in retention and accumulation of low density lipoprotein (LDL) in vessel intima and leading to atherosclerosis development. This study inve...

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Detalles Bibliográficos
Autores principales: Babaahmadi-Rezaei, Hossein, Kheirollah, Alireza, Rashidi, Mojtaba, Seif, Faezeh, Niknam, Zahra, Zamanpour, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588823/
https://www.ncbi.nlm.nih.gov/pubmed/34837677
http://dx.doi.org/10.22074/cellj.2021.7392