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GPR Expression in Intestinal Biopsies From SCT Patients Is Upregulated in GvHD and Is Suppressed by Broad-Spectrum Antibiotics

Microbiota can exert immunomodulatory effects by short-chain fatty acids (SCFA) in experimental models of graft-versus-host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (allo-SCT). Therefore we aimed to analyze the expression of SCFAs sensing G-protein coupled receptor GPR...

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Detalles Bibliográficos
Autores principales: Ghimire, Sakhila, Weber, Daniela, Hippe, Katrin, Meedt, Elisabeth, Hoepting, Matthias, Kattner, Anna-Sophia, Hiergeist, Andreas, Gessner, André, Matos, Carina, Ghimire, Saroj, Wolff, Daniel, Edinger, Matthias, Hoffmann, Petra, Poeck, Hendrik, Herr, Wolfgang, Holler, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588834/
https://www.ncbi.nlm.nih.gov/pubmed/34777363
http://dx.doi.org/10.3389/fimmu.2021.753287