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Preparation and physicochemical characterization of sildenafil cocrystals

Sildenafil is a specific inhibitor of the phosphodiesterase type 5 (PDE-5) enzyme that protects cyclic guanosine monophosphate from breakdown by PDE-5. It is a biopharmaceutical categorization system Class II medication with low bioavailability because it is almost insoluble in water. The objectives...

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Detalles Bibliográficos
Autores principales: Sawatdee, Somchai, Atipairin, Apichart, Rakkummerd, Supitchaya, Suriyaphol, Onsinee, Harding, David J., Muenraya, Poowadon, Harding, Phimphaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588911/
https://www.ncbi.nlm.nih.gov/pubmed/34820318
http://dx.doi.org/10.4103/japtr.japtr_72_21