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Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function

Classical dendritic cells (cDCs) in mice have been divided into 2 major subsets based on the expression of nuclear transcription factors: a CD8(+)Irf8(+)Batf3 dependent (DC1) subset, and a CD8(-)Irf4(+) (DC2) subset. We found that the CD8(+)DC1 subset can be further divided into CD8(+)DC1a and CD8(+...

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Detalles Bibliográficos
Autores principales: Hongo, David, Zheng, Pingping, Dutt, Suparna, Pawar, Rahul D., Meyer, Everett, Engleman, Edgar G., Strober, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589020/
https://www.ncbi.nlm.nih.gov/pubmed/34777358
http://dx.doi.org/10.3389/fimmu.2021.746469