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Evaluation of protein kinase D auto-phosphorylation as biomarker for NLRP3 inflammasome activation

BACKGROUND: The NLRP3 inflammasome is a critical component of sterile inflammation, which is involved in many diseases. However, there is currently no known proximal biomarker for measuring NLRP3 activation in pathological conditions. Protein kinase D (PKD) has emerged as an important NLRP3 kinase t...

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Detalles Bibliográficos
Autores principales: Heiser, Diane, Rubert, Joëlle, Unterreiner, Adeline, Maurer, Claudine, Kamke, Marion, Bodendorf, Ursula, Farady, Christopher J., Roediger, Ben, Bornancin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589197/
https://www.ncbi.nlm.nih.gov/pubmed/34767572
http://dx.doi.org/10.1371/journal.pone.0248668