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Evaluation of protein kinase D auto-phosphorylation as biomarker for NLRP3 inflammasome activation
BACKGROUND: The NLRP3 inflammasome is a critical component of sterile inflammation, which is involved in many diseases. However, there is currently no known proximal biomarker for measuring NLRP3 activation in pathological conditions. Protein kinase D (PKD) has emerged as an important NLRP3 kinase t...
Autores principales: | Heiser, Diane, Rubert, Joëlle, Unterreiner, Adeline, Maurer, Claudine, Kamke, Marion, Bodendorf, Ursula, Farady, Christopher J., Roediger, Ben, Bornancin, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589197/ https://www.ncbi.nlm.nih.gov/pubmed/34767572 http://dx.doi.org/10.1371/journal.pone.0248668 |
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