Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes

No vaccine to protect against an estimated 238,000 shigellosis deaths per year is widely available. S. sonnei is the most prevalent Shigella, and multiple serotypes of S. flexneri, which change regionally and globally, also cause significant disease. The leading Shigella vaccine strategies are based...

Descripción completa

Detalles Bibliográficos
Autores principales: Citiulo, Francesco, Necchi, Francesca, Mancini, Francesca, Rossi, Omar, Aruta, Maria Grazia, Gasperini, Gianmarco, Alfini, Renzo, Rondini, Simona, Micoli, Francesca, Rappuoli, Rino, Saul, Allan, Martin, Laura B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589205/
https://www.ncbi.nlm.nih.gov/pubmed/34644291
http://dx.doi.org/10.1371/journal.pntd.0009826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589205/
https://www.ncbi.nlm.nih.gov/pubmed/34644291
http://dx.doi.org/10.1371/journal.pntd.0009826

Ejemplares similares