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Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development

Mutations in the G protein–coupled receptor GPR126/ADGRG6 cause human diseases, including defective peripheral nervous system (PNS) myelination. To study GPR126 function, we generated new genetic mice and zebrafish models. Murine Gpr126 is expressed in developing heart endocardium, and global Gpr126...

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Detalles Bibliográficos
Autores principales: Torregrosa-Carrión, Rebeca, Piñeiro-Sabarís, Rebeca, Siguero-Álvarez, Marcos, Grego-Bessa, Joaquím, Luna-Zurita, Luis, Fernandes, Vitor Samuel, MacGrogan, Donal, Stainier, Didier Y. R., de la Pompa, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589310/
https://www.ncbi.nlm.nih.gov/pubmed/34767447
http://dx.doi.org/10.1126/sciadv.abj5445