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Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development
Mutations in the G protein–coupled receptor GPR126/ADGRG6 cause human diseases, including defective peripheral nervous system (PNS) myelination. To study GPR126 function, we generated new genetic mice and zebrafish models. Murine Gpr126 is expressed in developing heart endocardium, and global Gpr126...
Autores principales: | Torregrosa-Carrión, Rebeca, Piñeiro-Sabarís, Rebeca, Siguero-Álvarez, Marcos, Grego-Bessa, Joaquím, Luna-Zurita, Luis, Fernandes, Vitor Samuel, MacGrogan, Donal, Stainier, Didier Y. R., de la Pompa, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589310/ https://www.ncbi.nlm.nih.gov/pubmed/34767447 http://dx.doi.org/10.1126/sciadv.abj5445 |
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