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High-resolution structure and dynamics of mitochondrial complex I—Insights into the proton pumping mechanism

Mitochondrial NADH:ubiquinone oxidoreductase (complex I) is a 1-MDa membrane protein complex with a central role in energy metabolism. Redox-driven proton translocation by complex I contributes substantially to the proton motive force that drives ATP synthase. Several structures of complex I from ba...

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Detalles Bibliográficos
Autores principales: Parey, Kristian, Lasham, Jonathan, Mills, Deryck J., Djurabekova, Amina, Haapanen, Outi, Yoga, Etienne Galemou, Xie, Hao, Kühlbrandt, Werner, Sharma, Vivek, Vonck, Janet, Zickermann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589321/
https://www.ncbi.nlm.nih.gov/pubmed/34767441
http://dx.doi.org/10.1126/sciadv.abj3221