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Intelligent host engineering for metabolic flux optimisation in biotechnology
Optimising the function of a protein of length N amino acids by directed evolution involves navigating a ‘search space’ of possible sequences of some 20(N). Optimising the expression levels of P proteins that materially affect host performance, each of which might also take 20 (logarithmically space...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589332/ https://www.ncbi.nlm.nih.gov/pubmed/34673920 http://dx.doi.org/10.1042/BCJ20210535 |