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Intelligent host engineering for metabolic flux optimisation in biotechnology

Optimising the function of a protein of length N amino acids by directed evolution involves navigating a ‘search space’ of possible sequences of some 20(N). Optimising the expression levels of P proteins that materially affect host performance, each of which might also take 20 (logarithmically space...

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Detalles Bibliográficos
Autores principales:	Munro, Lachlan J., Kell, Douglas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589332/ https://www.ncbi.nlm.nih.gov/pubmed/34673920 http://dx.doi.org/10.1042/BCJ20210535

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