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Development and characterization of a unique anti‐IgE mouse monoclonal antibody cross‐reactive between human and canine IgE

BACKGROUND: The efficacy assessment of human anti‐IgE monoclonal antibodies (mAbs) in animal models before clinical trials is hampered due to the lack of cross‐reactivity of anti‐IgE mAbs between species. OBJECTIVE: We developed CRE‐DR (an anti‐dog IgE monoclonal antibody), an anti‐IgE mouse mAb tha...

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Detalles Bibliográficos
Autores principales: Kumagai, Akiko, Nara, Takuya, Uematsu, Mizuho, Kakinuma, Yoko, Saito, Takashi, Masuda, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589357/
https://www.ncbi.nlm.nih.gov/pubmed/34533288
http://dx.doi.org/10.1002/iid3.531