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Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice

INTRODUCTION: Soluble forms of cytokine receptors can be involved in the endogenous regulation of cytokine activity. Soluble interleukin 7 receptor α (sCD127) naturally binds IL‐7, therefore there is interest in its potential application as an immunotherapeutic agent to regulate IL‐7. With the hypot...

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Detalles Bibliográficos
Autores principales: Aloufi, Nawaf A., Ali, Alaa K., Burke Schinkel, Stephanie C., Molyer, Bengisu, Barros, Priscila O., McBane, Joanne E., Lee, Seung‐Hwan, Angel, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589376/
https://www.ncbi.nlm.nih.gov/pubmed/34525268
http://dx.doi.org/10.1002/iid3.530