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Machine learning gene expression predicting model for ustekinumab response in patients with Crohn's disease

BACKGROUND: Recent studies reported the responses of ustekinumab (UST) for the treatment of Crohn's disease (CD) differ among patients, while the cause was unrevealed. The study aimed to develop a prediction model based on the gene transcription profiling of patients with CD in response to UST....

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Detalles Bibliográficos
Autores principales: He, Manrong, Li, Chao, Tang, Wanxin, Kang, Yingxi, Zuo, Yongdi, Wang, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589399/
https://www.ncbi.nlm.nih.gov/pubmed/34469062
http://dx.doi.org/10.1002/iid3.506