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Structural biology of human telomerase: progress and prospects
Telomerase ribonucleoprotein was discovered over three decades ago as a specialized reverse transcriptase that adds telomeric repeats to the ends of linear eukaryotic chromosomes. Telomerase plays key roles in maintaining genome stability; and its dysfunction and misregulation have been linked to di...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Portland Press Ltd.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589416/ https://www.ncbi.nlm.nih.gov/pubmed/34623385 http://dx.doi.org/10.1042/BST20200042 |