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Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease

Parkinson's disease (PD) is the second most prevalent late-onset neurodegenerative disorder worldwide after Alzheimer's disease for which available drugs only deliver temporary symptomatic relief. Loss of dopaminergic neurons (DaNs) in the substantia nigra and intracellular alpha-synuclein...

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Detalles Bibliográficos
Autor principal: Volpato, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589426/
https://www.ncbi.nlm.nih.gov/pubmed/34581766
http://dx.doi.org/10.1042/BST20210128