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Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer
The discovery of a new class of small molecule compounds that target the BCL-2 family of anti-apoptotic proteins is one of the great success stories of basic science leading to translational outcomes in the last 30 years. The eponymous BCL-2 protein was identified over 30 years ago due to its associ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589430/ https://www.ncbi.nlm.nih.gov/pubmed/34515749 http://dx.doi.org/10.1042/BST20210749 |