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Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells

The global health burden due to sepsis and the associated cytokine storm is substantial. While early intervention has improved survival during the cytokine storm, those that survive can enter a state of chronic immunoparalysis defined by transient lymphopenia and functional deficits of surviving cel...

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Detalles Bibliográficos
Autores principales: Jensen, Isaac J, Li, Xiang, McGonagill, Patrick W, Shan, Qiang, Fosdick, Micaela G, Tremblay, Mikaela M, Houtman, Jon CD, Xue, Hai-Hui, Griffith, Thomas S, Peng, Weiqun, Badovinac, Vladimir P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589447/
https://www.ncbi.nlm.nih.gov/pubmed/34652273
http://dx.doi.org/10.7554/eLife.70989