Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

B-cell receptor (BCR)-mediated antigen internalization and presentation are essential for humoral memory immune responses. Antigen encountered by B-cells is often tightly associated with the surface of pathogens and/or antigen-presenting cells. Internalization of such antigens requires myosin-mediat...

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Detalles Bibliográficos
Autores principales: Maeda, Fernando Y, van Haaren, Jurriaan JH, Langley, David B, Christ, Daniel, Andrews, Norma W, Song, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589448/
https://www.ncbi.nlm.nih.gov/pubmed/34704555
http://dx.doi.org/10.7554/eLife.66984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589448/
https://www.ncbi.nlm.nih.gov/pubmed/34704555
http://dx.doi.org/10.7554/eLife.66984

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