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Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF-κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis

Osteoarthritis (OA) is a chronic, progressive and degenerative disease, and its incidence is increasing on a yearly basis. However, the pathological mechanism of OA at each stage is still unclear. The present study aimed to explore the underlying mechanism of dihydroartemisinin (DHA) in terms of its...

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Detalles Bibliográficos
Autores principales: Ding, Dong, Yan, Jiangbo, Feng, Gangning, Zhou, Yong, Ma, Long, Jin, Qunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589459/
https://www.ncbi.nlm.nih.gov/pubmed/34738623
http://dx.doi.org/10.3892/ijmm.2021.5059