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Shenjinhuoxue Mixture Attenuates Inflammation, Pain, and Cartilage Degeneration by Inhibiting TLR-4 and NF-κB Activation in Rats with Osteoarthritis: A Synergistic Combination of Multitarget Active Phytochemicals

Osteoarthritis (OA), a highly prevalent chronic joint disease, involves a complex network of inflammatory mediators that not only triggers pain and cartilage degeneration but also accelerates disease progression. Traditional Chinese medicinal shenjinhuoxue mixture (SHM) shows anti-inflammatory and a...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoqin, Hao, Chenxia, Zhang, Zhaokang, Jiang, Huiting, Zhang, Weixia, Huang, Jingjing, Chen, Xiaofei, Yang, Wanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589511/
https://www.ncbi.nlm.nih.gov/pubmed/34777686
http://dx.doi.org/10.1155/2021/4190098