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Shenjinhuoxue Mixture Attenuates Inflammation, Pain, and Cartilage Degeneration by Inhibiting TLR-4 and NF-κB Activation in Rats with Osteoarthritis: A Synergistic Combination of Multitarget Active Phytochemicals
Osteoarthritis (OA), a highly prevalent chronic joint disease, involves a complex network of inflammatory mediators that not only triggers pain and cartilage degeneration but also accelerates disease progression. Traditional Chinese medicinal shenjinhuoxue mixture (SHM) shows anti-inflammatory and a...
Autores principales: | Ma, Xiaoqin, Hao, Chenxia, Zhang, Zhaokang, Jiang, Huiting, Zhang, Weixia, Huang, Jingjing, Chen, Xiaofei, Yang, Wanhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589511/ https://www.ncbi.nlm.nih.gov/pubmed/34777686 http://dx.doi.org/10.1155/2021/4190098 |
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