Regulation of PCSK9 Expression and Function: Mechanisms and Therapeutic Implications

Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes degradation of low-density lipoprotein receptor (LDLR) and plays a central role in regulating plasma levels of LDL cholesterol levels, lipoprotein(a) and triglyceride-rich lipoproteins, increasing the risk of cardiovascular disease. Addi...

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Detalles Bibliográficos
Autores principales: Xia, Xiao-dan, Peng, Zhong-sheng, Gu, Hong-mei, Wang, Maggie, Wang, Gui-qing, Zhang, Da-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589637/
https://www.ncbi.nlm.nih.gov/pubmed/34782856
http://dx.doi.org/10.3389/fcvm.2021.764038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589637/
https://www.ncbi.nlm.nih.gov/pubmed/34782856
http://dx.doi.org/10.3389/fcvm.2021.764038

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