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Interferon and anti-TNF therapies differentially modulate amygdala reactivity which predicts associated bidirectional changes in depressive symptoms

A third of patients receiving Interferon-α (IFN-α) treatment for Hepatitis-C develop major depressive disorder (MDD). Conversely, anti-Tumor Necrosis Factor (TNF) therapies improve depression providing key empirical support for the “inflammatory theory” of depression. Heightened amygdala reactivity...

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Detalles Bibliográficos
Autores principales: Davies, Kevin A., Cooper, Ella, Voon, Valerie, Tibble, Jeremy, Cercignani, Mara, Harrison, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589643/
https://www.ncbi.nlm.nih.gov/pubmed/32457424
http://dx.doi.org/10.1038/s41380-020-0790-9