Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants

Copy number variants (CNVs) are associated with syndromic and severe neurological and psychiatric disorders (SNPDs), such as intellectual disability, epilepsy, schizophrenia, and bipolar disorder. Although considered high-impact, CNVs are also observed in the general population. This presents a diag...

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Detalles Bibliográficos
Autores principales: Saarentaus, Elmo Christian, Havulinna, Aki Samuli, Mars, Nina, Ahola-Olli, Ari, Kiiskinen, Tuomo Tapio Johannes, Partanen, Juulia, Ruotsalainen, Sanni, Kurki, Mitja, Urpa, Lea Martta, Chen, Lei, Perola, Markus, Salomaa, Veikko, Veijola, Juha, Männikkö, Minna, Hall, Ira M., Pietiläinen, Olli, Kaprio, Jaakko, Ripatti, Samuli, Daly, Mark, Palotie, Aarno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589645/
https://www.ncbi.nlm.nih.gov/pubmed/33526825
http://dx.doi.org/10.1038/s41380-021-01026-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589645/
https://www.ncbi.nlm.nih.gov/pubmed/33526825
http://dx.doi.org/10.1038/s41380-021-01026-z

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