PAI-1 protein is a key molecular effector in the transition from normal to PTSD-like fear memory

Moderate stress increases memory and facilitates adaptation. In contrast, intense stress can induce pathological memories as observed in post-traumatic stress disorders (PTSD). A shift in the balance between the expression of tPA and PAI-1 proteins is responsible for this transition. In conditions o...

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Detalles Bibliográficos
Autores principales: Bouarab, C., Roullot-Lacarrière, V., Vallée, M., Le Roux, A., Guette, C., Mennesson, M., Marighetto, A., Desmedt, A., Piazza, P. V., Revest, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589667/
https://www.ncbi.nlm.nih.gov/pubmed/33510345
http://dx.doi.org/10.1038/s41380-021-01024-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589667/
https://www.ncbi.nlm.nih.gov/pubmed/33510345
http://dx.doi.org/10.1038/s41380-021-01024-1

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