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PAI-1 protein is a key molecular effector in the transition from normal to PTSD-like fear memory
Moderate stress increases memory and facilitates adaptation. In contrast, intense stress can induce pathological memories as observed in post-traumatic stress disorders (PTSD). A shift in the balance between the expression of tPA and PAI-1 proteins is responsible for this transition. In conditions o...
Autores principales: | Bouarab, C., Roullot-Lacarrière, V., Vallée, M., Le Roux, A., Guette, C., Mennesson, M., Marighetto, A., Desmedt, A., Piazza, P. V., Revest, J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589667/ https://www.ncbi.nlm.nih.gov/pubmed/33510345 http://dx.doi.org/10.1038/s41380-021-01024-1 |
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