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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder

Bipolar disorder is a chronic neuropsychiatric condition associated with mood instability, where patients present significant sleep and circadian rhythm abnormalities. Currently, the pathophysiology of bipolar disorder remains elusive, but treatment with lithium continues as the benchmark pharmacoth...

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Detalles Bibliográficos
Autores principales: Sanghani, Harshmeena R., Jagannath, Aarti, Humberstone, Thomas, Ebrahimjee, Farid, Thomas, Justyn M., Churchill, Grant C., Cipriani, Andrea, Attenburrow, Mary-Jane, Perestenko, Olga V., Cowley, Sally A., Cader, M. Zameel, Peirson, Stuart N., Harrison, Paul J., Foster, Russell G., Goodwin, Guy M., Vasudevan, Sridhar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589670/
https://www.ncbi.nlm.nih.gov/pubmed/32404948
http://dx.doi.org/10.1038/s41380-020-0769-6