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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder
Bipolar disorder is a chronic neuropsychiatric condition associated with mood instability, where patients present significant sleep and circadian rhythm abnormalities. Currently, the pathophysiology of bipolar disorder remains elusive, but treatment with lithium continues as the benchmark pharmacoth...
Autores principales: | Sanghani, Harshmeena R., Jagannath, Aarti, Humberstone, Thomas, Ebrahimjee, Farid, Thomas, Justyn M., Churchill, Grant C., Cipriani, Andrea, Attenburrow, Mary-Jane, Perestenko, Olga V., Cowley, Sally A., Cader, M. Zameel, Peirson, Stuart N., Harrison, Paul J., Foster, Russell G., Goodwin, Guy M., Vasudevan, Sridhar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589670/ https://www.ncbi.nlm.nih.gov/pubmed/32404948 http://dx.doi.org/10.1038/s41380-020-0769-6 |
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