Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males

The mammalian SWI/SNF nucleosome remodeler is essential for spermatogenesis. Here, we identify a role for ARID2, a PBAF (Polybromo - Brg1 Associated Factor)-specific subunit, in meiotic division. Arid2(cKO) spermatocytes arrest at metaphase-I and are deficient in spindle assembly, kinetochore-associ...

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Detalles Bibliográficos
Autores principales: Menon, Debashish U., Kirsanov, Oleksandr, Geyer, Christopher B., Magnuson, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589837/
https://www.ncbi.nlm.nih.gov/pubmed/34772938
http://dx.doi.org/10.1038/s41467-021-26828-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589837/
https://www.ncbi.nlm.nih.gov/pubmed/34772938
http://dx.doi.org/10.1038/s41467-021-26828-1

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