Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
The mammalian SWI/SNF nucleosome remodeler is essential for spermatogenesis. Here, we identify a role for ARID2, a PBAF (Polybromo - Brg1 Associated Factor)-specific subunit, in meiotic division. Arid2(cKO) spermatocytes arrest at metaphase-I and are deficient in spindle assembly, kinetochore-associ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589837/ https://www.ncbi.nlm.nih.gov/pubmed/34772938 http://dx.doi.org/10.1038/s41467-021-26828-1 |