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HLA-G gene editing in tumor cell lines as a novel alternative in cancer immunotherapy

Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients remain unresponsive to them. Hence, the development of novel clinical immunothera...

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Detalles Bibliográficos
Autores principales: Palma, María Belén, Tronik-Le Roux, Diana, Amín, Guadalupe, Castañeda, Sheila, Möbbs, Alan M., Scarafia, María Agustina, La Greca, Alejandro, Daouya, Marina, Poras, Isabelle, Inda, Ana María, Moro, Lucía N., Carosella, Edgardo D., García, Marcela N., Miriuka, Santiago G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589947/
https://www.ncbi.nlm.nih.gov/pubmed/34773056
http://dx.doi.org/10.1038/s41598-021-01572-0