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Cromolyn platform suppresses fibrosis and inflammation, promotes microglial phagocytosis and neurite outgrowth

Neurodegenerative diseases are characterized by chronic neuroinflammation and may perpetuate ongoing fibrotic reactions within the central nervous system. Unfortunately, there is no therapeutic available that treats neurodegenerative inflammation and its sequelae. Here we utilize cromolyn, a mast ce...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Jun, Downey, Matthew A., Choi, Sungwoon, Shoup, Timothy M., Elmaleh, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589953/
https://www.ncbi.nlm.nih.gov/pubmed/34772945
http://dx.doi.org/10.1038/s41598-021-00465-6