Cargando…
Cromolyn platform suppresses fibrosis and inflammation, promotes microglial phagocytosis and neurite outgrowth
Neurodegenerative diseases are characterized by chronic neuroinflammation and may perpetuate ongoing fibrotic reactions within the central nervous system. Unfortunately, there is no therapeutic available that treats neurodegenerative inflammation and its sequelae. Here we utilize cromolyn, a mast ce...
Autores principales: | Wang, Yi-Jun, Downey, Matthew A., Choi, Sungwoon, Shoup, Timothy M., Elmaleh, David R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589953/ https://www.ncbi.nlm.nih.gov/pubmed/34772945 http://dx.doi.org/10.1038/s41598-021-00465-6 |
Ejemplares similares
-
Cromolyn Reduces Levels of the Alzheimer’s Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis
por: Zhang, Can, et al.
Publicado: (2018) -
Cromolyn inhibits the secretion of inflammatory cytokines by human microglia (HMC3)
por: Wang, Yi-Jun, et al.
Publicado: (2021) -
Pharmacokinetics of Cromolyn and Ibuprofen in Healthy Elderly Volunteers
por: Brazier, David, et al.
Publicado: (2017) -
The Role of Bioactive Compounds on the Promotion of Neurite Outgrowth
por: More, Sandeep Vasant, et al.
Publicado: (2012) -
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos
por: He, Bing-Qiang, et al.
Publicado: (2023)