Interferon mediated prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine lacking non-structural protein 1

The influenza A non-structural protein 1 (NS1) is known for its ability to hinder the synthesis of type I interferon (IFN) during viral infection. Influenza viruses lacking NS1 (ΔNS1) are under clinical development as live attenuated human influenza virus vaccines and induce potent influenza virus-s...

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Detalles Bibliográficos
Autores principales: Rathnasinghe, Raveen, Salvatore, Mirella, Zheng, Hongyong, Jangra, Sonia, Kehrer, Thomas, Mena, Ignacio, Schotsaert, Michael, Muster, Thomas, Palese, Peter, García-Sastre, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589955/
https://www.ncbi.nlm.nih.gov/pubmed/34773048
http://dx.doi.org/10.1038/s41598-021-01780-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589955/
https://www.ncbi.nlm.nih.gov/pubmed/34773048
http://dx.doi.org/10.1038/s41598-021-01780-8

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