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Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining

DNA double-strand breaks (DSBs) are among the most deleterious types of DNA damage as they can lead to mutations and chromosomal rearrangements, which underlie cancer development. Classical non-homologous end-joining (cNHEJ) is the dominant pathway for DSB repair in human cells, involving the DNA-bi...

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Detalles Bibliográficos
Autores principales: Singh, Jenny Kaur, Smith, Rebecca, Rother, Magdalena B., de Groot, Anton J. L., Wiegant, Wouter W., Vreeken, Kees, D’Augustin, Ostiane, Kim, Robbert Q., Qian, Haibin, Krawczyk, Przemek M., González-Prieto, Román, Vertegaal, Alfred C. O., Lamers, Meindert, Huet, Sébastien, van Attikum, Haico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589989/
https://www.ncbi.nlm.nih.gov/pubmed/34772923
http://dx.doi.org/10.1038/s41467-021-26691-0