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Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining
DNA double-strand breaks (DSBs) are among the most deleterious types of DNA damage as they can lead to mutations and chromosomal rearrangements, which underlie cancer development. Classical non-homologous end-joining (cNHEJ) is the dominant pathway for DSB repair in human cells, involving the DNA-bi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589989/ https://www.ncbi.nlm.nih.gov/pubmed/34772923 http://dx.doi.org/10.1038/s41467-021-26691-0 |