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Impact of ceftolozane/tazobactam concentrations in continuous infusion against extensively drug-resistant Pseudomonas aeruginosa isolates in a hollow-fiber infection model

Ceftolozane/tazobactam (C/T) has emerged as a potential agent for the treatment of extensively drug-resistant (XDR) Pseudomonas aeruginosa infections. As it is a time-dependent antimicrobial, prolonged infusion may help achieve pharmacokinetic/pharmacodynamic (PK/PD) targets. To compare alternative...

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Detalles Bibliográficos
Autores principales: Montero, María M., Domene-Ochoa, Sandra, López-Causapé, Carla, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, Padilla, Eduardo, Prim, Núria, Ferrer-Alapont, Lorena, Angulo-Brunet, Ariadna, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589991/
https://www.ncbi.nlm.nih.gov/pubmed/34773066
http://dx.doi.org/10.1038/s41598-021-01784-4