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Impact of ceftolozane/tazobactam concentrations in continuous infusion against extensively drug-resistant Pseudomonas aeruginosa isolates in a hollow-fiber infection model
Ceftolozane/tazobactam (C/T) has emerged as a potential agent for the treatment of extensively drug-resistant (XDR) Pseudomonas aeruginosa infections. As it is a time-dependent antimicrobial, prolonged infusion may help achieve pharmacokinetic/pharmacodynamic (PK/PD) targets. To compare alternative...
Autores principales: | Montero, María M., Domene-Ochoa, Sandra, López-Causapé, Carla, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, Padilla, Eduardo, Prim, Núria, Ferrer-Alapont, Lorena, Angulo-Brunet, Ariadna, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589991/ https://www.ncbi.nlm.nih.gov/pubmed/34773066 http://dx.doi.org/10.1038/s41598-021-01784-4 |
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