Unraveling the stepwise maturation of the yeast telomerase including a Cse1 and Mtr10 mediated quality control checkpoint

Telomerases elongate the ends of chromosomes required for cell immortality through their reverse transcriptase activity. By using the model organism Saccharomyces cerevisiae we defined the order in which the holoenzyme matures. First, a longer precursor of the telomerase RNA, TLC1 is transcribed and...

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Detalles Bibliográficos
Autores principales: Hirsch, Anna Greta, Becker, Daniel, Lamping, Jan-Philipp, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590012/
https://www.ncbi.nlm.nih.gov/pubmed/34773052
http://dx.doi.org/10.1038/s41598-021-01599-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590012/
https://www.ncbi.nlm.nih.gov/pubmed/34773052
http://dx.doi.org/10.1038/s41598-021-01599-3

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