Cargando…

Unraveling the stepwise maturation of the yeast telomerase including a Cse1 and Mtr10 mediated quality control checkpoint

Telomerases elongate the ends of chromosomes required for cell immortality through their reverse transcriptase activity. By using the model organism Saccharomyces cerevisiae we defined the order in which the holoenzyme matures. First, a longer precursor of the telomerase RNA, TLC1 is transcribed and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirsch, Anna Greta, Becker, Daniel, Lamping, Jan-Philipp, Krebber, Heike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590012/ https://www.ncbi.nlm.nih.gov/pubmed/34773052 http://dx.doi.org/10.1038/s41598-021-01599-3

Ejemplares similares

Fission yeast mtr1p regulates interphase microtubule cortical dwell-time
por: Carlier-Grynkorn, Frédérique, et al.
Publicado: (2014)

Maturation and shuttling of the yeast telomerase RNP: assembling something new using recycled parts
por: Bartle, Louise, et al.
Publicado: (2021)

Non-canonical Roles of Telomerase: Unraveling the Imbroglio
por: Ségal-Bendirdjian, Evelyne, et al.
Publicado: (2019)

The MTN and MTR bending magnets
por: Keizer, Reinder L, et al.
Publicado: (1978)

Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast
por: Mishra, Prashant K., et al.
Publicado: (2021)

Methylation of CENP-A/Cse4 on arginine 143 and lysine 131 regulates kinetochore stability in yeast
por: Tran Nguyen, Tra My, et al.
Publicado: (2023)

Stepwise maturation of the peptidyl transferase region of human mitoribosomes
por: Lenarčič, Tea, et al.
Publicado: (2021)

Structural basis for MTR4–ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex
por: Puno, M. Rhyan, et al.
Publicado: (2018)

Correction for Jiang et al., Kinetics of trifurcated electron flow in the decaheme bacterial proteins MtrC and MtrF
Publicado: (2022)

Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast
por: Hewawasam, Geetha S, et al.
Publicado: (2018)

Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast
por: Hewawasam, Geetha S, et al.
Publicado: (2018)

The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore
por: Fischböck-Halwachs, Josef, et al.
Publicado: (2019)

Structure and mechanism of the methyltransferase ribozyme MTR1
por: Scheitl, Carolin P.M., et al.
Publicado: (2022)

Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells
por: Armstrong, Christine A., et al.
Publicado: (2017)

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H(2)S Signaling via DNA Hypermethylation of CSE Promoter
por: Li, Jiao-Jiao, et al.
Publicado: (2015)

Telomerase Activation after Recruitment in Fission Yeast
por: Armstrong, Christine Anne, et al.
Publicado: (2014)

Peculiarities of Yeasts and Human Telomerase RNAs Processing
por: Rubtsova, M.P., et al.
Publicado: (2016)

The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo
por: Henikoff, Steven, et al.
Publicado: (2014)

Stepwise assembly of the earliest precursors of large ribosomal subunits in yeast
por: Chen, Wu, et al.
Publicado: (2017)

Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
por: Vidal-Cardenas, Sofia L., et al.
Publicado: (2010)

Overview of key findings on CSE status in 4 countries
por: Ivanova, O
Publicado: (2023)

Trypanosome MTR4 is involved in rRNA processing
por: Cristodero, Marina, et al.
Publicado: (2007)

Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in Neisseria gonorrhoeae
por: Zalucki, Yaramah M., et al.
Publicado: (2012)

Regulated assembly and disassembly of the yeast telomerase quaternary complex
por: Tucey, Timothy M., et al.
Publicado: (2014)

The RNA helicases Dbp2 and Mtr4 regulate the expression of Xrn1-sensitive long non-coding RNAs in yeast
por: Wery, Maxime, et al.
Publicado: (2023)

Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces
por: Hu, Xichan, et al.
Publicado: (2016)

Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation
por: Noureen, Nighat, et al.
Publicado: (2021)

Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum
por: Huang, Jingwen, et al.
Publicado: (2021)

Stepwise Splitting of Ribosomal Proteins from Yeast Ribosomes by LiCl
por: Piir, Kerli, et al.
Publicado: (2014)

Stepwise and dynamic assembly of the earliest precursors of small ribosomal subunits in yeast
por: Zhang, Liman, et al.
Publicado: (2016)

Unraveling the Role of Immune Checkpoints in Leishmaniasis
por: de Freitas e Silva, Rafael, et al.
Publicado: (2021)

HP-UX CSE: official study guide and desk reference
por: Keenan, Charles
Publicado: (2005)

Scientific style and format: the CSE manual for authors, editors, and publishers
por: Council of Science Editors
Publicado: (2014)

Centromere-specific histone Cse4 by the chaperone Scm3
por: Cho, Uhn-Soo, et al.
Publicado: (2013)

Skeletal Muscle CSE Deficiency Leads to Insulin Resistance in Mice
por: Xu, Miaomiao, et al.
Publicado: (2022)

Translation of SERAT findings into concrete steps to advance CSE in Georgia
por: Bandzeladze, M
Publicado: (2023)

Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE
por: Tamburrino, Giulia, et al.
Publicado: (2017)

Scm3 deposits a (Cse4–H4)(2) tetramer onto DNA through a Cse4–H4 dimer intermediate
por: Dechassa, Mekonnen Lemma, et al.
Publicado: (2014)

1440. The Genetic Basis for a Neisseria gonorrhoeae Clinical Isolate That Contains mtrR(-79) Mutation But Is Highly Susceptible to Antibiotics Effluxed by the Mtr Pump System
por: Huang, Jianzhong, et al.
Publicado: (2020)

Fission yeast Ccq1 is a modulator of telomerase activity
por: Armstrong, Christine A, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_09i2ku3emvk6q00qp5ajftasie